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After dropping Ronnie Brown, Ricky Williams had no troubles choosing up the ball and carry it for more than a hundred yards and a pair of touchdowns and an acquiring touchdown. Chad Henne is appearing to be successful and the offense is obtaining more powerful as the 12 months continues. Buffalo, on the other hand, hasn"t appeared to be doing much on either side of the ball. Their defense isn"t receiving the work accomplished. The offense has a wide receiver, but no one to throw the ball to him. Soon after posting a 197 yard game, Terrell Owens seems as though he can be the wristband maker this week, but Fitzpatrick needs to get the ball to him 1st. Then Chiefs pulled a likely surprise and picked the defensive lineman from LSU, Tyson Jackson. An absolute stud, who had reminded numerous teams of last year LSU senior and Chiefs number 1 draft select final 12 months, Glen Doresy. The two Doresy and Jackson attended LSU and could put a great complement to one another in the Chiefs defensive outlook for this upcoming season. There are plenty of diverse fundraisers you can run with cheerleading squads. You could do an eco-pleasant fundraiser in which you sell environmentally friendly merchandise. The Jamba Juice fundraiser is well-liked with several cheerleading teams. You could also promote customized bracelets, and then there are several seasonal fundraising tips you could investigate also. Your really initial camp is rather hectic. You are sort of thrown into the fire. Clearly large school is a lot distinct then university. Guys are bigger, more rapidly and more powerful. Coming into an offense like this is a large leap. Substantial school to freshman 12 months is huge. Going into your sophomore year you adapt a tiny bit far more. Last but not least it is time for me now, I am a junior, it is time for me to go. It is GO time! I really feel like I have the playbook down and like I stated before I am just making an attempt to play fast. If you presently have a near-fitting dress with a flared skirt, you can make an inexpensive and straightforward 50s Halloween costume. Nonetheless, you might also be able to discover this sort of dress very cheaply at a thrift retailer. Locate a white apron, a standard belt, a little white scarf and white gloves. Fashion your hair into tight curls by wearing sponge rollers overnight. Put on pearl earrings, studs or clip-ons. Tie the scarf close to your neck and make up your encounter with a tiny basis and tons of encounter powder with red lipstick, light eyeshadow and mascara. Dress in nude hose and high heeled pumps. Carry equipment this kind of as a spatula, a rolling pin or a broom to make your 50s housewife costume comprehensive.

 

Luiz Philipe, who was born with microcephaly, sleeps in his house in Marica, Rio de Janeiro state, Brazil, on March 9, 2016. Brazil will adopt the World Health Organization (WHO) standards from the next week to determine if a baby has microcephaly, the Brazilian Health Ministry said on Wednesday. [Photo/Xinhua]


WASHINGTON -- Chinese researchers said Thursday they might have solved the mystery of why the Zika virus causes microcephaly, a birth defect marked by small head size that can lead to severe developmental problems in babies.

In a study published in the US journal Science, a team led by Cheng-Feng Qin of the Beijing Institute of Microbiology and Epidemiology reported that one single genetic change, likely acquired in 2013, gave the mosquito-borne virus the ability to cause severe fetal microcephaly.

"Our findings offer a reasonable explanation for the unexpected causal link of Zika to microcephaly, and will help understand how Zika evolved from an innocuous mosquito-borne virus into a congenital pathogen with global impact," Qin said.

Zika was first identified in 1947 in Uganda, and until its recent emergence in the Americas, was a little known one that sporadically causes mild infections.

Then, it rapidly swept through South and Central America in 2015, and due to its link to congenital brain abnormalities, especially microcephaly during pregnancy, the World Health Organization declared in early 2016 the current epidemics a public health emergency of international concern.

However, scientists remain unable to determine why the virus evolved into a pathogen triggering severe neurological syndromes.

By comparing contemporary Zika virus strains from the 2015 and 2016 South American epidemics with an ancestral Cambodian virus that was circulating in 2010, Qin and colleagues found one critical mutation that conferred the ability to cause microcephaly in mouse models of fetal infection.

That one change, S139N, which replaced a serine amino acid with an asparagine at the 139th position of a Zika protein called prM, also made the virus more lethal to human neuron precursor cells in culture compared with the ancestral form.

Zika accumulated numerous changes throughout its genome between 2010 and 2016, of which S139N caused substantially more severe microcephaly and embryonic lethality in mouse models.

Evolutionary analyses revealed that the S139N change likely arose sometime around 2013, which coincided with initial reports of microcephaly.

It was then stably maintained during subsequent spread to the America.

"The discovery should provide guidance for the study of pathogenetic mechanisms of the Zika virus and for the development of vaccines and treatments," Qin said.